MethPlus

• Acts as a factor in the optimization of amino acid nutrition of animals and poultry.
  
• Includes active ingredients that are involved in biochemical reactions of activation and re-synthesis of methionine.
• Reduces the non-productive costs of the amino acid methionine in intermediate metabolism, reduces its losses in the process of catabolism
• Provides active synthesis of cysteine ​​and taurine with minimal consumption of methionine.
• Supports normal liver function (reduces AST and ALT), increasing the terms of economic exploitation of animals and poultry.

Active substances and their sources in the product:

Specially prepared (with functional additives) inactivated brewer's yeast (10%) is a source of folate (H4-folate), folic acid, serine, glycine, choline, catalysts (vitamins B, especially B12).

Legume flour (20%) is a rich source of folates (H4-folate), folic acid, betaine, serine, dimethylglycine.

In the composition of at least 10% carob flour, as a source of vitamin and protein ingredients to increase the absorption of methionine in the gastrointestinal tract. Due to their positive effect on the work of the digestive tract (when mixed with liquid, they contribute to the formation of a useful colloidal gel, help to relax the intestinal walls and improve the absorption of nutrients).

Specialized additives:

Algae (10%) is an alternative, rich source of methyl groups.

Extract of red grape and anise leaves (7.5%) - natural flavors, flavor enhancers with high antioxidant and anti-inflammatory properties (as an equivalent of the anti-inflammatory effect of methionine and its metabolite: S-Adenosyl-methionine).

Methionine is activated in the liver:

1) With the help of catalysts and methyl donors:

Folate + Serine; Betaine; Alternative sources of methyl groups (dimethylglycine, choline, 5 methyl THFA, etc.).

2) Using catalysts:

vitamin B12 - the main catalyst, carrier of methyl groups;

Н4folate - folic acid in the liver is converted into Н4folate in several stages with the participation of enzymes; vitamin B6 - activates the process of transsulfation (formation of cysteine);

3) With the help of the enzymes MAT I and MAT III (methionine adenosyl triphosphatase) with the participation of methyl groups, SAM (S-adenosyl methionine), the active formamethionine, is synthesized. Under the action of methyl agents, the rate and volume of cystine synthesis from methionine increases 1.5-1.7 times, the consumption of methionine decreases by 50%;

4) Provided there is a sufficient concentration of activators-nutrients, the volume of SAM synthesis increases by 2 times. Consequently, the need for methionine intake with feed falls by 30-40%.

In addition to the diet, without changing it:

• For optimal growth, feed conversion, protein and energy metabolism in broilers, laying hens and breeders.
• To increase the safety and productivity of farm animals.
• For strengthening and maintaining the immune system of animals and poultry.
• To improve the reproductive function of animals.
• To stimulate hunting in replacement animals to optimize the age of first insemination.
• For optimal growth, feed conversion, protein and energy metabolism in monogastric and ruminants

Diet methionine replacement, recipe optimization:

• It is used in feeding animals and poultry in order to partially, adequately replace the synthetic methionine additive and obtain economic benefits by optimizing the cost of the ration (reducing the cost of compound feed recipes).
• The product allows you to significantly improve the conversion of feed, optimize production efficiency indicators.
• MethPlus allows you to replace 25 to 75% synthetic DL-methionine in your diet.

It is thermostable, does not lose activity during granulation and extruding under normal conditions.

In addition to the diet, without changing it:

• pigs, poultry - 0.5-1.0 kg / ton of feed
• ruminants - 10-25 g / head per day

Replacement of methionine in the diet, optimization of the recipe. Equivalence:

• DL-methionine 1: 1 MethPlus
• Hydroxyanalogue of methionine OH-methionine-L 1,2: 1 MethPlus
• MHA-methionine 1.3: 1 MethPlus